The application process for The Prototyping Grant 2019 has now been closed.

Shamim Ahmmed

Combining the Pieces in Microfluidics for Personalized Cancer Therapy

Combining the Pieces in Microfluidics for Personalized Cancer Therapy

Personalized cancer therapy is a treatment strategy based on the ability to predict which patients are more likely to respond to specific cancer therapies1. Different factors such as tumor biophysical markers, tumor site, patient genetic factors, and characteristics need to be considered in determining a specific therapy for a patient. Tumor biophysical markers including phenotypes and genotypes are associated with patient prognosis and response to therapy as phenotypes like size, shape, stiffness of individual cells within a tumor can be correlated with the state of the disease and genotypic information from DNA, RNA and protein sequencing can reveal genomic alterations. Moreover, patient genetic factors are also important as they can be associated with drug metabolism, drug toxicity, and overall drug response. (more…)