Meet The Prototyping Grant Winner 2019!

Mohammad Ali Zoljalali

Microfluidic Heat Exchanger, a Unique Solution for Cooling of the Latest Electronic Devices

Microfluidic Heat Exchanger, a Unique Solution for Cooling of the Latest Electronic Devices

When a lot of electro-mechanical systems have been miniaturized and integrated by compact design, thermal management in a small volume should be simultaneously considered. As the devices or systems become smaller, heat flux increases in general. Therefore, an effective cooling strategy for the micro-devices is required especially when the cooling target is made from microfabrication processes. The microfluidic heat exchanger is one of the most promising devices for cooling down the electronic systems because it can be also made by the microfabrication processes1. This device which is also called microchannel heat sink has been considered as an effective heat removal tool and has caught much attention during the past decades, due to its advantages including high heat transfer performance, mild pressure loss and easy fabrication2. (more…)

How is Microfluidics Used in Aging Research?

How is Microfluidics Used in Aging Research?

Aging has been always a significant concern for mankind and they have been seeking a solution to overcome this challenge from the beginning. Biology as a scientific method presents important approaches which can revolutionize aging studies. Approaches that improve understanding of the underlying molecular mechanisms of aging, as well as their contributions to age-associated diseases. Studying the replicative aging phenomenon in the budding yeast has led to significant findings on how aging is regulated by evolutionarily conserved enzymes and molecular pathways. Identifying and characterizing the factors that modulate longevity is central to understanding the basic mechanisms of aging. Among model organisms used for research related to aging, the budding yeast has proven to be an important system for defining pathways that influence lifespan. Replicative lifespan is defined by the number of daughter cells a mother cell can produce before senescing. Over the past 10 years, replicative life span analysis has been performed on several thousand yeast strains, identifying several hundred genes that influence replicative longevity.1 (more…)