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Posts Tagged "biological research"

How Did Microfluidics Change Biological Research?

How Did Microfluidics Change Biological Research?

In conventional laboratories, a range of available technologies enables scientists to genetically engineer cells, study their migration patterns, determine their mechanical properties and even analyze genetic differences. Nevertheless, protocols for such experiments are set in place by standard equipment and commercial kits, often requiring considerable labor and cost. Although some degree of flexibility is permitted in the alteration of certain parameters, results could be compromised by such change. As such, most biologists are typically averse to making changes to their setup. Performing experiments has thus far meant using gold standard instruments from established pharmaceutical and biotechnological companies. For example, one could start their day preparing 10 L of media for culturing microorganisms in a large chemostat; use a DNA extraction kit to lyse the cells, numerous rounds of centrifugation; DNA purification; proceed on to amplification and target detection using a benchtop real-time Polymerase Chain Amplification (rt-PCR) machine. However, consider this. What if a device the size of a standard laboratory glass slide is able to accomplish these steps from cell culture to mutation identification in half the time and perhaps even half the cost? (more…)