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Posts Tagged "aging research"

How is Microfluidics Used in Aging Research?

How is Microfluidics Used in Aging Research?

Aging has been always a significant concern for mankind and they have been seeking a solution to overcome this challenge from the beginning. Biology as a scientific method presents important approaches which can revolutionize aging studies. Approaches that improve understanding of the underlying molecular mechanisms of aging, as well as their contributions to age-associated diseases. Studying the replicative aging phenomenon in the budding yeast has led to significant findings on how aging is regulated by evolutionarily conserved enzymes and molecular pathways. Identifying and characterizing the factors that modulate longevity is central to understanding the basic mechanisms of aging. Among model organisms used for research related to aging, the budding yeast has proven to be an important system for defining pathways that influence lifespan. Replicative lifespan is defined by the number of daughter cells a mother cell can produce before senescing. Over the past 10 years, replicative life span analysis has been performed on several thousand yeast strains, identifying several hundred genes that influence replicative longevity.1 (more…)