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Archive for February, 2018

Microfluidics and male fertility

Microfluidics and male fertility

Infertility is an ever-increasing public health concern. More than 70 million couples worldwide have experienced infertility issues at least once in their life. This number is one out of each six couples in Canada and Australia. In contrast to many other health concerns, such as Malaria and HIV/AIDS, that mostly affect low-resource settings, infertility is a much bigger concern in developed countries. Notably, in countries such as Canada, USA, UK, Australia, and those in the European Union, the current birth rate per family is far below the threshold of 2.1 to maintain their populations at current levels1. This low birth rate together with the rising trend of infertility point towards a significant aging problem in the near future, which is already a considerable concern for governments and policymakers around the world. Male and female partners each account for ~45% of infertility cases. In the case of male infertility, the issue arises from the incapability of sperm, as a microswimmer, to propagate through the microenvironment of the female reproductive tract to reach the egg and fertilize it. Sperm analysis and selection are crucial to male infertility diagnosis and treatment. However, current clinical methods for semen analysis are costly, and conventional sperm selection approaches are far from the natural process in vivo. (more…)

Microfluidics, meet superbugs

Microfluidics, meet superbugs

When my friends and family ask about my research, and I reply ‘microfluidics’, they always look confused and say, ‘Okay, what is that?’ This is not surprising since I didn’t know the word three years ago. The general public knows about scientific research in certain areas, like cancer, global warming, artificial intelligence and virtual reality. They either are problems we consider important or have applications we can relate to. But in the case of microfluidics, a distinct ‘feature’ is that its fame is mostly restricted to labs that deal with it. But if a technology were to be converted to productivity, people should know something about it, otherwise, they will not become users.

Commercialization of microfluidics has been a point of interest for a long time and has many researchers within the field frustrated. Back in 2006, George Whitesides raised this question in his inspiring paper1, yet more than a decade later we don’t seem to have any good answer.Some say we need a ‘killer app’2, while others point to the gap between academia and industry3. Whatever the reason may be, we can all agree that commercialization is an important step which microfluidics as a technology hasn’t been able to take. (more…)